Solvent toxicity is a serious barrier to sustainable fabrication of polymeric membranes. This research introduces three dibasic esters (DBEs) as various membrane fabrication solvents which might be biodegradable, non-carcinogenic, non-corrosive, and non-hazardous. The usage of DBEs in fabrication course of shifts the monotectic level within the part diagram of PVDF/solvent techniques in direction of increased polymer concentrations, enabling membrane formation by liquid-liquid part inversion to supply a bicontinuous construction that confers excellent efficiency. The very best-performing membrane ready on this method had an distinctive flux of 42.40 kg/m²·h and a excessive rejection price (>99%) within the decontamination of artificial nuclear wastewater. In comparison with membranes ready beforehand utilizing poisonous and non-toxic solvents, membranes fabricated in DBEs exhibited superior mechanical efficiency resulting from their bicontinuous construction, which successfully distributes exterior forces all through the membrane. Furthermore, DBEs are cheaper than poisonous standard solvents and are available in bulk, making them engaging choices for industrial-scale membrane manufacturing.