Are you vulnerable to dropping as much as 20% of your bone within the years round menopause?  Girls with accelerated bone loss – known as “quick losers” in a brand new examine – run a better danger of growing osteoporosis and weaker bones than the typical girl. The typical girl solely loses 8-10% of her bone mass through the three years round menopause.

This new examine reveals there’s a simple method to discover out in case you’re a “quick loser” of bone so you’ll be able to take motion to cease it.

Discover out in case you’re a “quick loser” of bone

Researchers centered on the usage of the N-telopeptide crosslinks take a look at — a urine take a look at — to assist determine ladies most in danger for better and quicker bone loss.  As you lose bone, fragments of sure bone proteins present up within the urine; these are known as N-telopeptides (NTx). A lady with extra NTx protein fragments in her urine is probably going present process extra speedy bone loss, and thus at increased danger of extreme menopausal bone loss.

Within the examine, researchers seemed on the NTx bone breakdown ranges in some 500 early post-menopausal ladies who have been inside 1-2 years of getting their closing interval. They discovered the next:

• The upper the urinary NTx degree, the quicker the speed of bone loss throughout the menopausal transition. This is sensible: a better price of bone breakdown would seemingly translate into better bone loss.
• A urinary NTx degree above 65 nM BCE/mM Cr was discovered to determine quick bone losers pretty nicely. To place this into context, the typical premenopausal NTx degree is 36 nM BCE/mM Cr, and I’ve typically discovered postmenopausal ladies with a 50 NTx degree to be dropping ½ to 1% of bone mass per 12 months.
• The affiliation between early postmenopausal NTx and price of bone loss was stronger on the backbone than on the hip. This once more is sensible, as a result of the backbone is metabolically energetic trabecular bone, which typically loses mass years earlier than the hip does.
• Moreover, trying backwards, it was discovered {that a} excessive urinary NTx in perimenopause was additionally related to a better price of bone loss through the menopause transition.

Menopausal bone loss isn’t unfold evenly over the 10-year transitional interval (5 years earlier than a girl’s final interval and 5 years after).  Most bone loss happens within the 3-year interval beginning 1 12 months earlier than a girl’s final interval and ending 2 years after her final interval — referred to as “trans menopause.”

What does this analysis imply for you?

If you happen to’re noticing signs of perimenopause, like irregular durations and sizzling flashes or in case you underwent menopause just lately (inside a few years), a easy take a look at of your urine NTx degree will help you determine a bent to extreme bone loss.

If you happen to’re experiencing extreme bone loss, you’ll be able to take steps to seek out out why this may be so and proper the state of affairs. Once I work with particular person purchasers, that is precisely the kind of work I do with them.

Extra data on the straightforward urine take a look at might be present in my brief video and related handbook. You may also order this take a look at on-line by our on-line inquiry system at our lab companion Evexia.

And since you’ll be able to’t actually know when the 12 months earlier than your final interval will happen till you even have skilled your final interval, it’s a good suggestion to get began instantly on a powerful Higher Bones Program on the first indicators of perimenopause.

Reference:

Shieh A, et al.  Urinary N-telopeptide and price of bone loss over the menopause transition an early post-menopause. J Bone Miner Res. 2016;31(11):2057-2064.